Publications

The full list of publications can be found on Google Scholar .

2023

10. Single-Cell RNA Sequencing Unifies Developmental Programs of Esophageal and Gastric Intestinal Metaplasia. Nowicki-Osuch K.^, Zhuang L., Cheung T. S., Black E. L., Masqué-Soler N., Devonshire G., Redmond A.M., Freeman A., di Pietro M., Pilonis N., Januszewicz W., O'Donovan M., Tavaré S., Shields J. D., Fitzgerald R. C.^ Cancer Discov. 2023 Jun 2;13(6):1346-1363. doi: 10.1158/2159-8290.CD-22-0824.

2022

9. Multi-omic cross-sectional cohort study of pre-malignant Barrett's esophagus reveals early structural variation and retrotransposon activity. Katz-Summercorn, A. C.; Jammula, S.; Frangou, A.; Peneva, I.; O'Donovan, M.; Tripathi, M.; Malhotra, S.; Di Pietro, M.; Abbas, S.; Devonshire, G.; Januszewicz, W.;  Blasko, A.; Nowicki-Osuch, K.; MacRae, S.; Northrop, A.; Redmond, A. M.; Wedge, D. C.; Fitzgerald, R. C. Nat Commun 2022, 13 (1), 1407.

2021

8. Complexities in the role of acetylation dynamics in modifying inducible gene activation parameters. Carrera, S.; O'Donnell, A.; Li, Y.; Nowicki-Osuch, K.; Yang, S. H.; Baker, S. M.; Spiller, D.; Sharrocks, A. D. Nucleic Acids Res 2021, 49 (22), 12744-12756.

7. Molecular phenotyping reveals the identity of Barrett's esophagus and its malignant transitionNowicki-Osuch, K.*; Zhuang, L.*; Jammula, S.; Bleaney, C. W.; Mahbubani, K. T.; Devonshire, G.; Katz-Summercorn, A.; Eling, N.; Wilbrey-Clark, A.; Madissoon, E.; Gamble, J.; Di Pietro, M.; O'Donovan, M.; Meyer, K. B.; Saeb-Parsy, K.; Sharrocks, A. D.; Teichmann, S. A.; Marioni, J. C.; Fitzgerald, R. C. Science 2021, 373 (6556), 760-767. *These authors contributed equally to this work.

6. Tolerance to nascent protein misfolding stress requires fine-tuning of the cAMP/PKA pathway. Kritsiligkou, P.; Nowicki-Osuch, K.; Carter, Z.; Kershaw, C. J.; Creamer, D. R.; Weids, A. J.; Grant, C. M. J Biol Chem 2021, 296, 100690.

2020

5. The mutREAD method detects mutational signatures from low quantities of cancer DNA. Perner, J.*; Abbas, S*.; Nowicki-Osuch, K.*; Devonshire, G.;Eldridge, M. D.; Tavare, S.; Fitzgerald, R. C. Nat Commun 2020, 11 (1), 3166.

4. scRNA-seq assessment of the human lung, spleen, and esophagus tissue stability after cold preservation. Madissoon, E.; Wilbrey-Clark, A.; Miragaia, R. J.; Saeb-Parsy, K.; Mahbubani, K. T.; Georgakopoulos, N.; Harding, P.; Polanski, K.; Huang, N.; Nowicki-Osuch, K.; Fitzgerald, R. C.; Loudon, K. W.; Ferdinand, J. R.; Clatworthy, M. R.; Tsingene, A.; van Dongen, S.; Dabrowska, M.; Patel, M.; Stubbington, M. J. T.; Teichmann, S. A.; Stegle, O.; Meyer, K. B. Genome Biol 2020, 21 (1), 1.

2019

3. How Deep Are the Roots of Barrett's Esophagus? Nowicki-Osuch, K.; Di Pietro, M. Gastroenterology 2019, 156 (6), 1928-1930.

2. Inflammatory pathways are central to posterior cerebrovascular artery remodelling prior to the onset of congenital hypertension. Walas, D.; Nowicki-Osuch, K.; Alibhai, D.; von Linstow Roloff, E.; Coghill, J.; Waterfall, C.; Paton, J. F. J Cereb Blood Flow Metab 2019, 39 (9), 1803-1817.

2017

1. EINCR1 is an EGF inducible lincRNA overexpressed in lung adenocarcinomasNowicki-Osuch, K.; Li, Y.; Challinor, M.; Gerrard, D. T.; Hanley, N. A.; Sharrocks, A. D. PLoS One 2017, 12 (7), e0181902.

* - equal contribution

^ - corresponding authors